J.S. Finer-Moore: search on Z-Library

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1

A Single Mutation Traps a Half-Sites Reactive Enzyme in Midstream, Explaining Asymmetry in Hydride Transfer

Finer-Moore, Janet S., Lee, Tom T., Stroud, Robert M.

Journal:

Year:

2018

Language:

english

File:

PDF, 6.72 MB

english, 2018

2

The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis

Sprang, S, Standing, T, Fletterick, R., Stroud, R., Finer-Moore, J, Xuong, N., Hamlin, R, Rutter, W., Craik, C.

Journal:

Year:

1987

Language:

english

File:

PDF, 1.64 MB

english, 1987

3

Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion

Rosenberg, Oren S., Dovala, Dustin, Li, Xueming, Connolly, Lynn, Bendebury, Anastasia, Finer-Moore, Janet, Holton, James, Cheng, Yifan, Stroud, Robert M., Cox, Jeffery S.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.39 MB

english, 2015

4

Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1

Alexei V Korennykh, Pascal F Egea, Andrei A Korostelev, Janet Finer-Moore, Robert M Stroud, Chao Zhang, Kevan M Shokat, Peter Walter

Journal:

Year:

2011

Language:

english

File:

PDF, 1.38 MB

english, 2011

5

Structural studies of .alpha.-bungarotoxin. 3. Corrections in the primary sequence and x-ray structure and characterization of an isotoxic .alpha.-bungarotoxin

Kosen, Phyllis Anne, Finer-Moore, Janet, McCarthy, Michael P., Basus, Vladimir J.

Journal:

Year:

1988

Language:

english

File:

PDF, 924 KB

english, 1988

6

Structure of a TrmA-RNA complex: A consensus RNA fold contributes to substrate selectivity and catalysis in m5U methyltransferases

Alian, A., Lee, T. T., Griner, S. L., Stroud, R. M., Finer-Moore, J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 1.76 MB

english, 2008

7

ChemInform Abstract: A NOVEL REARRANGEMENT OF HETISINE, AND X-RAY CRYSTAL STRUCTURE OF THE MAJOR PRODUCT: TRANSFORMATION OF A DIHYDROXYBICYCLO(2.2.2)OCTANE SYSTEM TO AN ADAMANTANE-TYPE SKELETON

PELLETIER, S. W., MODY, N. V., FINER-MOORE, J., ATEYA, A.-M. M., SCHRAMM, L. C.

Journal:

Chemischer Informationsdienst

Year:

1981

File:

PDF, 114 KB

1981

8

Structure of sugar-bound LacY

Kumar, Hemant, Kasho, Vladimir, Smirnova, Irina, Finer-Moore, Janet S., Kaback, H. Ronald, Stroud, Robert M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.42 MB

english, 2014

9

Structures and possible functions of epoxypukalide and pukalide

J. C. Coll, B. F. Bowden, A. Heaton, P. J. Scheuer, M. K. W. Li, J. Clardy, G. K. Schulte, J. Finer-Moore

Journal:

Journal of Chemical Ecology

Year:

1989

Language:

english

File:

PDF, 679 KB

english, 1989

10

Refined Structures of Substrate-bound and Phosphate-bound Thymidylate Synthase from Lactobacillus casei

Janet Finer-Moore, Eric B. Fauman, Paul G. Foster, Kathy M. Perry, Daniel V. Santi, Robert M. Stroud

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 939 KB

1993

11

On the mechanism of sensing unfolded protein in the endoplasmic reticulum

Credle, J. J., Finer-Moore, J. S., Papa, F. R., Stroud, R. M., Walter, P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 1.29 MB

english, 2005

12

Crystal Structure of Thymidylate Synthase from T4 Phage: Component of a Deoxynucleoside Triphosphate-Synthesizing Complex

Finer-Moore, Janet S., Maley, Gladys F., Maley, Frank, Montfort, William R., Stroud, Robert M.

Journal:

Year:

1994

Language:

english

File:

PDF, 3.22 MB

english, 1994

13

Alanine Mutants of the Interface Residues of Human Thymidylate Synthase Decode Key Features of the Binding Mode of Allosteric Anticancer Peptides

Tochowicz, Anna, Santucci, Matteo, Saxena, Puneet, Guaitoli, Giambattista, Trande, Matteo, Finer-Moore, Janet, Stroud, Robert M., Costi, Maria P.

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 4.44 MB

english, 2015

14

Plastic adaptation toward mutations in proteins: Structural comparison of thymidylate synthases

Kathy M. Perry, Eric B. Fauman, Janet S. Finer-Moore, William R. Montfort, Gladys F. Maley, Frank Maley, Robert M. Stroud

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1990

Language:

english

File:

PDF, 2.38 MB

english, 1990

15

The unfolded protein response signals through high-order assembly of Ire1

Korennykh, Alexei V., Egea, Pascal F., Korostelev, Andrei A., Finer-Moore, Janet, Zhang, Chao, Shokat, Kevan M., Stroud, Robert M., Walter, Peter

Journal:

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

16

In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities

Czudnochowski, Nadine, Wang, Amy Liya, Finer-Moore, Janet, Stroud, Robert M.

Journal:

Journal of Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

17

Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi

Lohse, M. B., Rosenberg, O. S., Cox, J. S., Stroud, R. M., Finer-Moore, J. S., Johnson, A. D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.42 MB

english, 2014

18

Structural context shapes the aquaporin selectivity filter

David F. Savage, Joseph D. O'Connell III, Larry J. W. Miercke, Janet Finer-Moore and Robert M. Stroud

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.44 MB

english, 2010

19

Atomic structure of thymidylate synthase: target for rational drug design

Hardy, L., Finer-Moore, J., Montfort, W., Jones, M., Santi, D., Stroud, R.

Journal:

Year:

1987

Language:

english

File:

PDF, 2.14 MB

english, 1987

20

Crystal Structure of the Human tRNA m1A58 Methyltransferase–tRNA3Lys Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target

Finer-Moore, Janet, Czudnochowski, Nadine, O'Connell, Joseph D., Wang, Amy Liya, Stroud, Robert M.

Journal:

Journal of Molecular Biology

Year:

2015

Language:

english

File:

PDF, 3.82 MB

english, 2015

21

Entropy in Bi-substrate Enzymes: Proposed Role of an Alternate Site in Chaperoning Substrate into, and Products out of, Thymidylate Synthase

David L. Birdsall, Janet Finer-Moore, Robert M. Stroud

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 1.61 MB

english, 1996

22

ChemInform Abstract: COMPUTER-ASSISTED CARBON-13 NUCLEAR MAGNETIC RESONANCE SPECTRUM ANALYSIS AND STRUCTURE PREDICTION FOR THE C19-DITERPENOID ALKALOIDS

FINER-MOORE, J., MODY, N. V., PELLETIER, S. W., GRAY, N. A. B., CRANDELL, C. W., SMITH, D. H.

Journal:

Chemischer Informationsdienst

Year:

1982

File:

PDF, 106 KB

1982

23

Addendum: Multi-targeted Antifolates Aimed at Avoiding Drug Resistance Form Covalent Closed Inhibitory Complexes with Human and Escherichia coli Thymidylate Synthases

P.H. Sayre, J.S. Finer-Moore, T.A. Fritz, D. Biermann, S.B. Gates, W.C. MacKellar, V.F. Patel, R.M. Stroud

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 49 KB

english, 2002

24

Location of an extrinsic label in the primary and tertiary structure of bacteriorhodopsin

Katre, N.V., Finer-Moore, J., Stroud, R.M., Hayward, S.B.

Journal:

Biophysical Journal

Year:

1984

Language:

english

File:

PDF, 1.12 MB

english, 1984

25

Tryptophan 80 and Leucine 143 Are Critical for the Hydride Transfer Step of Thymidylate Synthase by Controlling Active Site Access †,‡

Fritz, Timothy A., Liu, Lu, Finer-Moore, Janet S., Stroud, Robert M.

Journal:

Year:

2002

Language:

english

File:

PDF, 679 KB

english, 2002

26

Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit

Pan, H., Agarwalla, S., Moustakas, D. T., Finer-Moore, J., Stroud, R. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2003

Language:

english

File:

PDF, 594 KB

english, 2003

27

ChemInform Abstract: AN ALUMINA CATALYZED ADDITION OF SECONDARY AMINES TO EXOCYCLIC α,β-UNSATURATED KETONES

PELLETIER, S. W., VENKOV, A. P., FINER-MOORE, J., MODY, N. V.

Journal:

Chemischer Informationsdienst

Year:

1980

File:

PDF, 120 KB

1980

28

An alumina catalyzed addition of secondary amines to exocyclic α,β-unsaturated ketones

S.William Pelletier, Atanas P. Venkov, Janet Finer-Moore, Naresh V. Mody

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 191 KB

english, 1980

29

Δ9(15)-Africanene, a new sesquiterpene hydrocarbon from the soft coralSinularia erecta

Y. Kashman, M. Bodner, Janet S. Finer-Moore, J. Clardy

Journal:

Cellular and Molecular Life Sciences

Year:

1980

Language:

english

File:

PDF, 206 KB

english, 1980

30

Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer

Christopher L. Reyes, Carleton R. Sage, Earl E. Rutenber, Robert M. Nissen, Janet S. Finer-Moore, Robert M. Stroud

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 2.11 MB

english, 1998

31

Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate [Erratum to document cited in CA113(7):54978v]

Montfort, William R., Perry, Kathy M., Fauman, Eric B., Finer-Moore, Janet S., Maley, Gladys F., Hardy, Larry, Maley, Frank, Stroud, Robert M.

Journal:

Year:

1990

Language:

english

File:

PDF, 66 KB

english, 1990

32

The only active mutant of thymidylate synthase D169, a residue far from the site of methyl transfer, demonstrates the exquisite nature of enzyme specificity

Birdsall, D. L., Finer-Moore, J., Stroud, R. M.

Journal:

Protein Engineering Design and Selection

Year:

2003

Language:

english

File:

PDF, 1.25 MB

english, 2003

33

EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins

Oren S. Rosenberg, Cole Dovey, Michael Tempesta, Rebecca A. Robbins, Janet S. Finer-Moore, Robert M. Stroud and Jeffery S. Cox

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.29 MB

english, 2011

34

Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides

Kapoor, Khyati, Finer-Moore, Janet S., Pedersen, Bjørn P., Caboni, Laura, Waight, Andrew, Hillig, Roman C., Bringmann, Peter, Heisler, Iring, Müller, Thomas, Siebeneicher, Holger, Stroud, Robert M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.56 MB

english, 2016

35

Partitioning Roles of Side Chains in Affinity, Orientation, and Catalysis with Structures for Mutant Complexes: Asparagine-229 in Thymidylate Synthase†,‡

Finer-Moore, Janet S., Liu, Lu, Schafmeister, Christian E., Birdsall, David L., Mau, Ted, Santi, Daniel V., Stroud, Robert M.

Journal:

Year:

1996

Language:

english

File:

PDF, 764 KB

english, 1996

36

Pairwise specificity and sequential binding in enzyme catalysis: thymidylate synthase

Finer-Moore, Janet S., Montfort, William R., Stroud, Robert M.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.21 MB

english, 1990

37

Asparagine 229 Mutants of Thymidylate Synthase Catalyze the Methylation of 3-Methyl-2‘-deoxyuridine 5‘-Monophosphate †

Costi, Paola M., Liu, Lu, Finer-Moore, Janet S., Stroud, Robert M., Santi, Daniel V.

Journal:

Year:

1996

Language:

english

File:

PDF, 440 KB

english, 1996

38

Substrate Recognition by RNA 5-Methyluridine Methyltransferases and Pseudouridine Synthases: A Structural Perspective

Hur, S., Stroud, R. M., Finer-Moore, J.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 770 KB

english, 2006

39

Replacement set mutagenesis of the four phosphate-binding arginine residues of thymidylate synthase

Kawase, S., Cho, S.-W., Rozelle, J., Stroud, R. M., Finer-Moore, J., Santi, D. V.

Journal:

Protein Engineering Design and Selection

Year:

2000

Language:

english

File:

PDF, 90 KB

english, 2000

40

Emblide, a new polyfunctional cembranolide from the soft coral sarcophyton glaucum

John A. Toth, B. Jay Burreson, Paul J. Scheuer, Janet Finer-Moore, Jon Clardy

Journal:

Year:

1980

Language:

english

File:

PDF, 242 KB

english, 1980

41

The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE

Hu Pan, Joseph D. Ho, Robert M. Stroud, Janet Finer-Moore

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 2.68 MB

english, 2007

42

A Novel dCMP Methylase by Engineering Thymidylate Synthase †

Agarwalla, Sanjay, LaPorte, Sherry, Liu, Lu, Finer-Moore, Janet, Stroud, Robert M., Santi, Daniel V.

Journal:

Year:

1997

Language:

english

File:

PDF, 509 KB

english, 1997

43

Episelection: Novel Ki .apprx. Nanomolar Inhibitors of Serine Proteases Selected by Binding or Chemistry on an Enzyme Surface

Katz, Bradley A., Finer-Moore, Janet, Mortezaei, Reza, Rich, Daniel H., Stroud, Robert M.

Journal:

Year:

1995

Language:

english

File:

PDF, 5.11 MB

english, 1995

44

Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase

Finer-Moore, Janet S., Fauman, Eric B., Morse, Richard J., Santi, Daniel V., Stroud, Robert M.

Journal:

Protein Engineering Design and Selection

Year:

1996

Language:

english

File:

PDF, 1.90 MB

english, 1996

45

The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs

Czudnochowski, N., Ashley, G. W., Santi, D. V., Alian, A., Finer-Moore, J., Stroud, R. M.

Journal:

Nucleic Acids Research

Year:

2014

Language:

english

File:

PDF, 8.82 MB

english, 2014

46

Ion transport and regulation in a synaptic vesicle glutamate transporter

Li, Fei, Eriksen, Jacob, Finer-Moore, Janet, Chang, Roger, Nguyen, Phuong, Bowen, Alisa, Myasnikov, Alexander, Yu, Zanlin, Bulkley, David, Cheng, Yifan, Edwards, Robert H., Stroud, Robert M.

Journal:

Year:

2020

File:

PDF, 1.17 MB

2020

47

The Role of Protein Dynamics in Thymidylate Synthase Catalysis: Variants of Conserved 2‘-Deoxyuridine 5‘-Monophosphate (dUMP)-Binding Tyr-261 †,‡

Newby, Zachary, Lee, Tom T., Morse, Richard J., Liu, Yaoquan, Liu, Lu, Venkatraman, Prasanna, Santi, Daniel V., Finer-Moore, Janet S., Stroud, Robert M.

Journal:

Year:

2006

Language:

english

File:

PDF, 1.14 MB

english, 2006

48

The structural roles of conserved Pro196, Pro197 and His199 in the mechanism of thymidylate synthase

Gonzalez-Pacanowska, D., Ruiz-Perez, L. M., Carreras-Gomez, M. A., Costi, M. P., Stroud, R. M., Finer-Moore, J., Santi, D. V.

Journal:

Protein Engineering Design and Selection

Year:

2003

Language:

english

File:

PDF, 338 KB

english, 2003

49

Diversity in kinetics correlated with structure in nano body-stabilized LacY

Kumar, Hemant, Finer-Moore, Janet, Smirnova, Irina, Kasho, Vladimir, Pardon, Els, Steyaert, Jan, Kaback, H. Ronald, Stroud, Robert M., van Veen, Hendrik W.

Journal:

Year:

2020

File:

PDF, 2.20 MB

2020

50

Lessons and Conclusions from Dissecting the Mechanism of a Bisubstrate Enzyme: Thymidylate Synthase Mutagenesis, Function, and Structure †

Finer-Moore, Janet S., Santi, Daniel V., Stroud, Robert M.

Journal:

Year:

2003

Language:

english

File:

PDF, 253 KB

english, 2003

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